CLEARANCE machine Anthony Miles is set to play his first match for Richmond against his former club Greater Western Sydney on Saturday.

After showing excellent signs in the VFL, Miles was promoted to the senior list on Tuesday.

The Tigers are battling several injury concerns ahead of the away clash with the Giants, who will welcome back a host of big names.

Tough Tigers utility Nick Vlastuin will miss 3-5 weeks with a broken finger, key defender David Astbury is unlikely to play again this season after dislocating his kneecap in the shock loss to Melbourne and captain Trent Cotchin faces a fitness test on his injured ankle.

A spot opened up for Miles when Jake King (foot) was placed on the long-term injury list and the Tigers upgraded Miles on Tuesday afternoon.

The 22-year-old has been averaging 30 possessions and nine clearances per game for the Tigers' reserves.

"Anthony has done everything right at VFL level since the start of the season and has well and truly earned his promotion to the senior list," said Richmond's general manager of football Dan Richardson.

"He's a hard worker, he loves the contested style of play, and he has fitted into the group extremely well since arriving at the club late last year.

"We're confident he'll grab his opportunity when it comes and make the most of it."

Miles played 10 games in two seasons with the Giants but was unable to nail down a regular senior berth.

The Tigers' season is in freefall, with the 17-point reverse to Melbourne seeing their win-loss record slip to 2-6.

Brett Deledio reaches the 200-game milestone against the Giants.

GWS should be strengthened by the return of spearhead Jeremy Cameron (perforated eardrum) and ruckman Shane Mumford (knee), while midfielder Adam Treloar and defender Curtly Hampton are also likely to be available after overcoming injuries.