BRISBANE midfielder and ex-Dockers star Lachie Neale is more relaxed about playing his old side the second time around despite having weeks to think about it.

Neale was a sensation in his first season at the Gabba last year but he doesn't count his 26-possession effort against Fremantle in round 10 among his highlights.

The Dockers are due to arrive in Queensland on Tuesday afternoon ahead of their round two clash with Chris Fagan's Lions as they prepare for at least a month-long stay in a Gold Coast resort.

"I feel pretty relaxed. Obviously these are unique circumstances at the moment but I feel really good," Neale said.

"Last time I was a lot more nervous and probably thought about the game too much before I played it and I had different things going on in my head.

"But this time I feel really relaxed and am just looking forward to playing, like the rest of the competition.

"I didn't play very well last time I played them and we lost by five points, so I certainly want to play better."

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Brisbane started the season with a disappointing loss to Hawthorn at the MCG and will be desperate to avoid an 0-2 start after finishing second in the home and away season a year ago.

The Lions are favourites to beat Fremantle but Neale said it was too early to tell what sort of advantage they'd enjoy over the clubs in the Gold Coast quarantine hub, including West Coast and eventually Port Adelaide and Adelaide.

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What he does know is Brisbane has a largely healthy list, with Marcus Adams (foot) and Irishman James Madden (quarantine) likely to be the only players unavailable.

Neale tipped Cam Rayner to play after hurting a knee in an intraclub hitout and having it strapped for training on Tuesday.

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Recruits Grant Birchall (hamstring soreness) and Callum Ah Chee (illness), who were late scratches for round one, and Cam Ellis-Yolmen are in line to make their club debut.

Stefan Martin (knee) has also recovered and will lead the Lions' ruck division against Sean Darcy and Rory Lobb.

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"He's put a lot of hard work in with his rehab over the break and he's always in good touch," Neale said of Martin. 

"I don't think that bloke leaves the gym – he's always in great physical condition – so he's ready to go. He played in that (intraclub) game and was all good."