ST KILDA has suffered a blow ahead of its must-win game with Carlton, losing Paddy Ryder as a late change.

The ruckman will miss Friday night’s clash with an Achilles injury having been off the training track this week. He has been replaced by Paul Hunter.

Carlton will go in as selected, meaning key pair Harry McKay and Charlie Curnow have been locked in to face the Saints. The Blues have named Marc Murphy as the medical substitute, which will be his 298th AFL game.

FOLLOW IT LIVE Saints v Blues

After a disappointing loss against cellar-dwellers North Melbourne, the heat is firmly on Blues coach David Teague and his team amid an external review into the club's prolonged poor performance.

The Blues have won seven games this year, and sit in 13th spot on the ladder.

HERE'S CHARLIE The must-watch thriller 761 days in the making

The Saints sit just one spot higher on the ladder with an 8-10 record, and must defeat the Blues to keep their very faint finals hopes alive.

02:32 Mins
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Match Previews R20: St Kilda v Carlton

Sportsbet's Nathan Brown and Matthew Richardson preview the game between the Saints and the Blues at Marvel Stadium

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St Kilda v Carlton at Marvel Stadium, 7.50pm AEST

LATE CHANGES
St Kilda: Paddy Ryder (Achilles) replaced in selected side by Paul Hunter

MEDICAL SUBS
St Kilda: Cooper Sharman
Carlton: Marc Murphy