LINGERING effects of concussion have forced Collingwood defender Ben Sinclair to withdraw from the Anzac Day clash with Essendon.

He will be replaced by fellow defender Brayden Maynard for the Monday afternoon clash at the MCG.

Sinclair's withdrawal means the Magpies will have made four changes to the team that lost to Melbourne in round four. 

Star forward Travis Cloke and fellow big man Jesse White were omitted, while defender Tom Langdon is out with a sore knee.

Cloke is set to play for Collingwood's VFL team against Essendon at Victoria Park from 2.10pm on Sunday.