FREMANTLE has named a shock debutant to replace injured captain Nat Fyfe for Sunday's Derby, while Alastair Clarkson has lost patience with a triple premiership Hawk.
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It comes as Port Adelaide ruckman Scott Lycett has succumbed to a knee injury and will miss Sunday's date with Carlton.
Dockers midfielder Michael Frederick, taken at pick 61 in last year's NAB AFL Draft – will play his first AFL match against West Coast, replacing the hamstrung Fyfe.
He will be joined in the Dockers' side by Brennan Cox who returns from a hip injury, while Eagles skipper Luke Shuey has been cleared after missing one week with his own hamstring.
At Hawthorn, Clarkson has dumped Paul Puopolo in place of forgotten small forward Darren Minchington who will make his Hawks debut and play his first AFL game since round 10, 2017.
The former Saint was delisted by the Hawks last season, recalled to training during summer, then told he was no longer required before earning a last-minute reprieve in March.
Veteran Shaun Burgoyne returns from a rest, while the Hawks have confirmed AFL.com.au's report that ruckman Jon Ceglar would miss with a broken toe despite naming him in the extended squad on Thursday.
Mitch Lewis is back from a hip injury to face the Demons who have recalled Luke Jackson, but left former skipper Nathan Jones and high-profile recruit Adam Tomlinson on the outer.
Lycett joins Brad Ebert (suspension) and Cameron Sutcliffe (hamstring) out of the Power's line-up to tackle Carlton, while Xavier Duursma returns and Sam Mayes will play his first AFL game in 757 days.
Tom Rockliff remains out of the Power's line-up for a second consecutive week.
Patrick Cripps and Marc Murphy have been named despite injury clouds, with the Blues taking in an unchanged line-up after last week's win over the Western Bulldogs.
Former captain Taylor Walker and maligned veteran Bryce Gibbs headline the list of inclusions in Adelaide's 26-man squad for Monday's clash with St Kilda.
Paul Seedsman could also earn a recall, while the Crows have named rookie ruckman and potential debutant Kieran Strachan with Billy Frampton dropped.
Rory Sloane will miss at least four weeks with a broken hand that required surgery midweek, opening the door for 23-year-old Tom Doedee to captain the club in his 27th game.
Saints midfielder Ryan Byrnes, taken at pick No.52 in last year's NAB AFL Draft, is a confirmed debutant and has been named in the squad with Ben Long (suspension) the only omission to date.
The final teams for the match at Adelaide Oval will be announced at 4.30pm AEST on Saturday.
Friday, July 17
Essendon v Western Bulldogs, Metricon Stadium, 7.50pm AEST
In: M.Redman, N.Cahill
Out: D.Shiel (suspension), M.Gleeson (managed)
New: Ned Cahill
In: H.Crozier, C.Weightman, M.Suckling, La.Young
Out: J.Schache (omitted), R.West (omitted), T.McLean (omitted), L.Butler (omitted)
New: Cody Weightman
Saturday, July 18
GWS v Brisbane, Giants Stadium, 1.45pm AEST
In: Z.Langdon, J.Caldwell, T.Taranto, B.Hill
Out: T.Green (omitted), C.Ward (knee), T.Greene (knee), D.Lloyd (managed)
Sydney v Gold Coast, SCG, 4.35pm AEST
In: A.Aliir, T.McCartin, E.Taylor, C.Sinclair
Out: H.McLean (omitted), S.Gray (omitted), I.Heeney (ankle), J.Kennedy (knee)
New: Elijah Taylor
Out: B.Fiorini (omitted)
Richmond v North Melbourne, Metricon Stadium, 7.40pm AEST
In: J.Ziebell, A.Bonar, M.Wood
Out: P.Ahern (hamstring), T.Campbell (omitted), T.Thomas (ankle)
Sunday, July 19
Carlton v Port Adelaide, Gabba, 1.05pm AEST
In: S.Mayes, X.Duursma, P.Ladhams
Out: C.Sutcliffe (hamstring), B.Ebert (suspension), S.Lycett (knee)
New: Sam Mayes
Hawthorn v Melbourne, Giants Stadium. 3.35pm AEST
In: S.Burgoyne, D.Minchington, M.Lewis
Out: J.Patton (hamstring), J.Ceglar (toe), P.Puopolo (omitted)
New: Darren Minchington
Out: T.McDonald (eye)
Fremantle v West Coast, Optus Stadium, 4.35pm AWST
In: B.Cox, M.Frederick
Out: N.Fyfe (hamstring), H.Young (ankle)
New: Michael Frederick
Out: B.Ainsworth (omitted)
Monday, July 20
Adelaide v St Kilda, Adelaide Oval, 7.10pm ACST
In: T.Walker, B.Gibbs, P.Seedsman, E.Himmelberg, B.Davis, K.Strachan
Out: R.Sloane (injured), B.Frampton (omitted)
In: P.Ryder, R.Byrnes, N.Hind, J.Sinclair, S.Savage
Out: B.Long (suspension)