MELBOURNE's task of overcoming its Simonds Stadium hoodoo just got tougher after the Demons withdrew star forward Jesse Hogan from the side to face Geelong on Sunday.

Hogan trained away from the main group on Friday morning and the Dees have cited hamstring tightness as the reason for leaving him out of the side.

"Jesse experienced some hamstring tightness during the game against St Kilda on Sunday. He's been monitored during the week and unfortunately hasn't been cleared," Demons football manager Josh Mahoney told on Friday afternoon.

"Considering we've got the bye next week, and he hasn't been cleared of his symptoms, we've decided not to risk Jesse."

The 20-year-old was one of the Demons' best player against St Kilda last Sunday, booting five goals.

Hogan was also a late withdrawal with back soreness for the club's game with Hawthorn in round seven. 

Mahoney said the Demons were confident Hogan's hamstring concern would not be a long-term issue and the club expects him to return against West Coast in round 14.

"This is a continuation of our plan to get Jesse through his first season of AFL football," Mahoney said. 

Since 1967, Melbourne has won just five of its 36 matches at Geelong. More recently, the Demons have won just one of their past 18 at the venue.

Sunday's game in Geelong will also mark Corey Enright's 300th match. 

Jordie McKenzie has been brought in as Hogan's replacement.