THE GREATEST modern-day rivalry will take another twist tonight when Hawthorn travels to Geelong in what will be superstar Patrick Dangerfield's 250th game.

>> FOLLOW IT LIVE FROM 7.50pm AEST

It is the first time the Hawks have played at GMHBA Stadium since 2006. In that outing, with Alastair Clarkson at the helm, Hawthorn thumped the home team by 52 points.

Both teams will line up as selected, with no late changes.

02:14 Mins
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Why a 'scary' Hawk could open up Cats

Neroli Meadows and Champion Data's Daniel Hoyne preview the Friday night matchup between Geelong and Hawthorn

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So much has happened since then between these powerhouses, including a grand tally of seven premiership cups shared between them.

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After losing to Greater Western Sydney in round one, the Cats will be desperate to get on the board for season 2020. Not only that, they will be super keen to celebrate Dangerfield's 250th in style.

01:17 Mins
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Match Preview: Geelong v Hawthorn

Nathan Brown and Matthew Richardson preview the Geelong v Hawthorn blockbuster at GMHBA Stadium

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Fremantle gets its first taste of life in Queensland when it takes on Brisbane at the Gabba on Saturday, before Harley Bennell's return headlines Melbourne's clash with Carlton.

ROUNDS 2-5 Check out the full fixture

The Showdown will fortunately take place in Adelaide on Saturday night, while the hub-based West Coast gets its first runout on Metricon Stadium when it meets Gold Coast.

Sunday brings more intriguing contests, as Greater Western Sydney gets to re-establish its premiership hopes against North Melbourne, round one victors Sydney and Essendon meet, and St Kilda plays the Western Bulldogs having both suffered disappointing first-up defeats.

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Tonight's clash begins at 7.50pm AEST. Follow it LIVE on AFL.com.au and the AFL Live Official App.