His Triple M co-host Luke Darcy was talking about the launch of a new stage show in Melbourne when the Collingwood president mentioned the dual Brownlow medalist.
It comes after McGuire played a key role in mending the damage following a 13-year-old Collingwood fan racially vilifying the Swans hero as an 'ape' at the MCG on Friday night.
Immediately after the match, McGuire met with Goodes in the Swans rooms and apologised for the incident.
Wednesday morning's on-air conversation played out as follows:
Darcy: What a great promo that is for King Kong.
McGuire: Get Adam Goodes down for it do you reckon?
Darcy: No I wouldn't have thought so, absolutely not.
McGuire: You can see them doing that can't you?
Darcy: What's that?
McGuire: You know with the ape thing, the whole thing, I'm just saying the pumping him up and mucking around and all that sort of stuff.
Soon afterwards, McGuire returned to air to clarify his comments.
"Just to clear up when we were talking about King Kong there and I was mumbling my way through about Goodsey.
"I was trying to say imagine the old days of trying to get people in for publicity.
"I mumbled my way through that, so anyone who thought that I was having a go or being a smart alec, I take that back.
"Neither do I, I was that exhausted this morning, so apologies for that.
"I was off on a tangent somewhere. Just in case people think 'What the hell's he on about?', I've got no idea either."