Prestigiacomo hasn't played a senior match since round 19, 2007 after being plagued by a serious foot injury.
But the 30-year-old is one of four changes to the Magpies team which will travel to Subiaco for Friday night’s round 22 clash with Fremantle.
Rhyce Shaw has won the faith of the selectors after serving a two-match club-imposed ban and an additional week in the reserves, adding further run to his in-form side, while youngsters Nathan Brown and Danny Stanley also come into Mick Malthouse’s team.
It wasn’t all good news for the Pies, however, with skipper Scott Burns among the most notable omissions.
The captain, as expected, will miss with his calf injury, while Shane Wakelin (groin), Sharrod Wellingham (groin) and Alan Toovey (foot) will also miss the trip west.
Fremantle has made just two changes for its 2008 swansong.
Clayton Hinkley and Andrew Browne get another chance to impress coach Mark Harvey, replacing omitted duo Steven Dodd and Brett Peake.
North Melbourne has named two important inclusions on the eve of its finals campaign, regaining small goalkicker Matt Campbell along with high-leaping forward Aaron Edwards.
Edwards hasn’t played since breaking his leg against the Sydney Swans in round six but has steadily upped his game time playing for North Ballarat in the VFL.
Jess Sinclair and Scott Thompson have both been omitted.
Port Adelaide key defender Troy Chaplin will have to watch his side’s final match of 2008 after a knee injury forced him out of Saturday’s clash with the Kangaroos at the MCG.
The promising Robbie Gray comes into the Power line-up to replace Chaplin as Mark Williams’ side tries to upset North and finish its miserable season on a bright note.
Geelong dropped one premiership forward for another as the Cats made two changes for Saturday’s round 22 clash with West Coast at Skilled Stadium.
Mathew Stokes, a late withdrawal from last week’s side that beat North Melbourne, will return along with Ryan Gamble as Mark Thompson named arguably his strongest 22 for the season.
Shannon Byrnes is an unlucky omission for Geelong, while Max Rooke will miss a match through suspension.
Tom Hawkins, who had been touted for a possible return, is among Geelong’s emergencies along with speedy defender David Wojcinski.
West Coast has brought in smart forward Mark LeCras, while former Geelong Falcon Will Schofield will return to the familiar surroundings of Skilled Stadium to take on the Cats.
Out of the side go Michael Braun, who farewelled AFL footy in front of the Subiaco crowd last week, and key position prospect Tony Notte.
Adelaide has recalled Jason Porplyzia, Bernie Vince and Kurt Tippett for Saturday’s clash with the Western Bulldogs at AAMI Stadium.
Star forward Porplyzia has not played since suffering brain bruising against Carlton on August 2, and has also been named despite an injury scare over his troublesome shoulder at training during the week.
Vince has missed two weeks with a hamstring strain and first-year forward Tippett earns a recall having not played for the Crows since round 17, and may also provide assistance in the ruck.
Brent Reilly, Brad Moran and Patrick Dangerfield make way for the trio. Adelaide can finish anywhere between fourth and eighth, depending on the result.
Whatever the outcome, the Western Bulldogs are destined for a finals meeting with Hawthorn, but they will want to go in with a win under their belt.
They have omitted Andrejs Everitt and Callan Ward, with Lindsay Gilbee returning to the side and young Queenslander Sam Reid to make his debut.
Reid was taken with pick 35 in last year's NAB AFL Draft, and is a hard-at-it midfielder who has impressed recently in the VFL with Williamstown.
Veteran midfielder Shane Crawford will be rested by Hawthorn for the clash with Carlton at Telstra Dome on Saturday night, while Simon Taylor (general soreness) is also missing.
The Hawks no doubt want their on-ball talisman fresh for the finals, but they won’t lose anything with the inclusions.
Luke Hodge returns after a one-week suspension for striking in the round 20 loss to Richmond and Robert Campbell is also back in the side after missing last week’s win over the Eagles in Perth with a virus.
There’s no change to the Carlton side which made a last-quarter surge to defeat the Brisbane Lions at the Gabba last week, and all eyes will be on Brendan Fevola and Hawthorn counterpart Buddy Franklin, who are both within reach of the magical 100-goal mark.
Fev needs eight more to reach the ton, but Franklin only needs two goals to be the first player to reach the milestone since Tony Lockett booted 107 (not including finals) in 1998 for the Sydney Swans.
Star Sydney Swans utility Adam Goodes has not recovered sufficiently from a groin injury to take his place, and will have the week off to be fresh for the finals.
Patrick Veszpremi has been omitted, while Luke Ablett and Nick Malceski come back into the selected 22.
The Brisbane Lions have made a raft of changes for their last match of the season against the Sydney Swans after they were knocked out of finals reckoning by the Blues last weekend.
Ash McGrath (quad) and Matthew Moody (groin) are out with injury, while Robert Copeland, James Hawksley, Travis Johnstone and Rhan Hooper have all been omitted.
There is little experience among most of the inclusions. Lachlan Henderson, Tom Collier, Albert Proud and Scott Clouston have played only 19 games between them. Scott Harding and Troy Selwood return to the senior team after impressing with the Suncoast Lions reserves side.
There will be a few tears shed by Melbourne fans with Demon veterans Adem Yze and Jeff White playing their last games for the club when it takes on Richmond at the MCG on Sunday.
Melbourne has made no fewer than seven changes to an extended squad of 25 as it tries to avoid winning the wooden spoon.
Jack Grimes will make his debut for the club after being taken at pick 14 in the 2007 NAB AFL Draft, while James Frawley, Addam Maric, Ricky Petterd, Shane Valenti, Ben Holland and veteran defender Nathan Carroll have also been named.
Explosive young forward Austin Wonaeamirri is out with a hamstring injury, while Mark Jamar, Matthew Bate and Lynden Dunn have all been omitted.
And experienced midfielder Greg Tivendale will play his 188th and last game for Richmond. It is only his third match of the season and the club has announced he will be delisted, while at the other end of a career, potential debutant Alex Rance has been included in an extended squad of 25.
West Australian Rance was taken with pick 18 in last year’s NAB AFL Draft. Adam Pattison and Dean Polo are the other two inclusions for the Tigers.
Essendon has named two potential first-gamers in its 25-man squad to tackle the Saints at Telstra Dome on Sunday.
The Bombers have added 19-year-old Queenslander John Williams and, despite already acknowledging that he’ll be discarded at the end of the season, the rookie-listed Danny Chartres.
The pair comes into the squad with Jarrod Atkinson, Leroy Jetta and impressive youngster Kyle Reimers.
The season is over for Adam McPhee (ankle) and Andrew Welsh (hamstring).
St Kilda has added three players – Jarryd Allen, David Armitage and Aaron Fiora – to its interchange for Sunday’s clash.
Both teams will finalise their squads on Friday night.
