WEST Coast stars Josh Kennedy and Jeremy McGovern could join Brad Sheppard and Tim Kelly on the sidelines as the Eagles count the cost of their Western Derby defeat.

Kelly will miss at least two to three weeks with a medial collateral ligament injury to his left knee.

It means he's unlikely to play again this year unless West Coast buck the odds and go deep in the finals.

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Sheppard has been ruled out of Saturday's must-win match against Brisbane at the Gabba after suffering a delayed concussion from last week's loss to Fremantle.

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Star Eagle goes down with knee injury

Tim Kelly is forced off the field after injuring his knee in this incident

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Kennedy bravely returned to the field after suffering a finger fracture that resulted in the bone piercing through the skin, but he's no certainty to front up against the Lions.

"Josh was pretty brave on the weekend," West Coast's general manager of football Craig Vozzo said.

"The knee actually held up really well from the week before, you might recall we had some trouble going into the game, and then unfortunately he had a fracture of the finger during the game, which was quite a nasty fracture.

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"We'll see how much ball handling he can do today and a little bit tomorrow and make a call from there."

McGovern is battling an ongoing hip injury.

"Jeremy has been playing very bravely for a large part of the year with a significant hip problem," Vozzo said.

"It's elevated over the last couple of weeks. He was very brave to get through the weekend.

Jeremy McGovern marks in round 22, 2021. Picture: AFL Photos

"We've got him doing some light duties today at training, see how he pulls up from there and we'll make a decision on selection after that."

Former skipper Shannon Hurn (hamstring) is still one or two weeks away from returning, while Liam Duggan's season is over after he underwent surgery on the posterior cruciate ligament in his knee.

Small forward Jamie Cripps, who lost several teeth after copping an accidental elbow from the Dockers' David Mundy, is expected to face the Lions.

Star goalsneak Willie Rioli, whose two-year ban ends on Friday, is looming as a strong chance to earn an immediate senior recall as West Coast launches one last effort to make the finals.

The ninth-placed Eagles (10-11) must beat Brisbane and hope either Greater Western Sydney loses to Carlton or Essendon loses to Collingwood in order to sneak into the top eight.