WEST Coast has finally regained All Australian ruckman Nic Naitanui, and the athletic big man will play his first game for the season when he lines up against the Western Bulldogs at Patersons Stadium this Sunday.

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Naitanui's return from a groin injury headlines the ins and outs for round six, with other notable selections including Andrew Krakouer at Collingwood, Brad Sewell at Hawthorn and Jarrad Waite at Carlton.

The Magpies have also named two debutants.

Regaining Naitanui is a big boost for the Eagles, who were one of the premiership favourites but have slumped to 1-4 after five rounds.

The Eagles have also brought in former Collingwood midfielder Sharrod Wellingham for his first game with the club.

Wellingham's debut has been delayed by an ankle injury he suffered on a trampoline during the pre-season.

Matt Rosa and Will Schofield have also been included in the Eagles' 25-man squad, with Sam Butler (calf) and Jamie Cripps (omitted) going out.

The Bulldogs have lost defender Brett Goodes to suspension, and they have recalled run-with player Dylan Addison.

Unbeaten Essendon has made four changes for its game against Greater Western Sydney at Etihad Stadium on Saturday afternoon.

Nick Kommer, who is back from suspension, comes in, as do Leroy Jetta, Tayte Pears and Jake Melksham.

Jason Winderlich (rested), Travis Colyer (omitted) , Dyson Heppell (groin) and Jake Carlisle (ankle) are out of the Bombers' side that beat Collingwood on Anzac Day.

The Giants, who have been hit hard by injuries to experienced players Phil Davis (back) and Setanta O'hAilpin (calf), have made seven changes in all.

Top draft picks Lachie Whitfield and Lachie Plowman have been given the weekend off.

Krakouer and ruckman Darren Jolly are the big names back in the Collingwood side, while first-gamers Ben Kennedy and Jarrod Witts have also been named.

Defender Alan Toovey (knee) and Ben Hudson (leg soreness) have been sidelined by injuries, while the Magpies have dropped Jordan Russell, Alex Fasolo and Ben Sinclair.

St Kilda has regained small forward Stephen Milne from suspension and have recalled Arryn Sipposs. The Saints have replaced Trent Dennis-Lane (omitted) and Tom Lee (achilles).

Will Sierakowski will make his debut for North Melbourne in the Roos' Saturday afternoon clash with Port Adelaide at Blundstone Arena in Hobart.

He has replaced midfielder Liam Anthony.

The Power has made just one change, with re-elevated rookie Kane Mitchell replacing key defender Jackson Trengove, who has been placed on the club's long-term injury list after needing foot surgery.

Adelaide has made three changes for its crucial clash with Hawthorn at AAMI Stadium on Saturday evening.

Key forward Taylor Walker, who suffered a serious knee injury last weekend, is the Crows' key out.

In a bid to bolster its attack, Adelaide has recalled two forwards, Jason Porplyzia and Shaun McKernan.

Sewell is the key inclusion for the Hawks, while former Geelong midfielder Jon Simpkin will play his first game for the club.

Richmond has regained defender Steve Morris from suspension for Saturday night's big clash with Geelong at the MCG.

Troy Chaplin and Jake King are also back in the Tigers' line-up after both missed the trip to Perth last weekend.

Brad Helbig is out with a hamstring injury, while Robin Nahas and Jake Batchelor have been dropped.

The Cats have regained premiership players Paul Chapman and Tom Hawkins, who were both rested from the clash with the Western Bulldogs last weekend.

Defender Jared Rivers is out for two months with a knee injury, while midfielder Josh Caddy, who was concussed against the Dogs, has been left out.

Gun midfielder Harley Bennell returns to the Gold Coast team for Saturday night's clash with Fremantle.

Fremantle has made four changes, with Paul Duffield, Alex Silvagni, Cameron Sutcliffe and Hayden Crozier replacing Kepler Bradley (knee), Stephen Hill (quad), Nathan Fyfe (suspension) and Lachie Neale (omitted).

The Sydney Swans have included Mitch Morton and Jesse White in their squad for Sunday's game against the Brisbane Lions at the SCG on Sunday morning.

The Lions have regained dynamic defender Pearce Hanley from suspension.

Waite is the key inclusion in the Blues' team to play Melbourne at the MCG on Sunday.

Elevated rookie Jaryd Cachia is also in the 25-man squad, but Bryce Gibbs is out with a hamstring problem.

The Demons have lost experienced campaigners Mark Jamar (groin), David Rodan (omitted) and Jack Watts (hamstring).

First-year midfielder Jack Viney and potential first-gamer Dean Kent are among the players who have come into the Dees' extended squad.