A full-time member of the integrity unit will be added this week, while two part-time employees will become full time.
Other staff and resources will be added in coming weeks.
At its meeting on Monday the Commission also agreed to adopt rules on mandatory reporting to the AFL of any doping activities or approaches and to enhance the registry of all club staff and personnel who have contact with players, including sports scientists.
It has also authorised an audit of backgrounds of all club employees, contractors and consultants.
In a statement, AFL CEO Andrew Demetriou said, "The Commission received an update from the executive on the development of a 'whistle-blower' policy which will be in place as soon as possible."
The League has written to each state and territory government seeking legislation to introduce information-sharing arrangements between police agencies, other investigative bodies and approved sporting bodies.
As well, it wants governments to adopt legislation that provides for a term of imprisonment for anyone found guilty of match fixing, similar to legislation adopted by the New South Wales Government last year.
And it has asked governments to legislate for the introduction of criminal sanctions for those who peddle and administer performance-enhancing drugs.
AFL medical directors will meet all club doctors over the next 10 days to review practices and the oversight of treatments, and clubs' use of supplements and other treatments will be audited.
Demetriou said the AFL Commission regarded the integrity of the game as its highest priority and the response and approach by the AFL would continue to evolve throughout this year.
"As far as the matters raised by the ACC apply to the AFL, they are being thoroughly investigated by ASADA (Australian Sports Anti-Doping Authority) and we will provide whatever support is required to ASADA and other agencies."